A non-steroidal selective androgen receptor modulator, studied under the name Testolone. 10mg × 60 per pack.
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RAD140 is a non-steroidal selective androgen receptor modulator (SARM): a small synthetic molecule with the formula C20H16ClN5O2, a molecular weight of about 393.8 g/mol and the CAS number 1182367-47-0. It was developed in 2010, first described in the literature in 2011, and has been studied under the research name Testolone. Selective androgen receptor modulators are built to bind the androgen receptor, the receptor testosterone acts through, with different strengths in different tissues, which is the property the field studies them for; they are not steroids in structure. In the published assays RAD140 is among the more potent and selective compounds of the group, and it is commonly researched in muscle and bone tissue models. Its formal human research has been in a different field: a small phase 1 study in 22 women with breast cancer, run from 2017 to 2020, with further early-stage trials in the same disease. It is not approved for any medical use. Case reports of liver injury in people using it outside trials have been published, and raised liver enzymes were common among the trial's participants. The World Anti-Doping Agency lists it by name among the prohibited SARMs. It is a small synthetic molecule rather than a peptide, so it is supplied dry rather than for reconstitution: 60 capsules of 10mg per pack.