A synthetic tuftsin analogue, usually studied in the same literature as Semax. 5mg per vial.
Selank is a synthetic heptapeptide, seven amino acids in the order Thr-Lys-Pro-Arg-Pro-Gly-Pro, with the molecular formula C33H57N11O9, a molecular weight of about 751.9 g/mol and the CAS number 129954-34-3. Its first four residues are tuftsin, a natural fragment of the antibody molecule IgG with a role in immune signalling; the last three are a proline-glycine-proline tail added for stability, the same stabilising tail used on Semax. It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, in the same research programme as Semax. It is commonly researched in models of anxiety and the stress response, and for its effects on the brain's monoamine systems, serotonin metabolism in particular, on brain-derived neurotrophic factor (BDNF) in the hippocampus, and on the enzymes that break down the body's own enkephalins. Its immune origin means it is also studied where the nervous and immune systems overlap, including its effect on interleukin-6 and other cytokines. Most of the findings come from animal studies, and the clinical data are limited. It is sold through pharmacies in Russia, but it is not a licensed medicine in the UK, the EU or the US. Supplied as 5mg of freeze-dried powder per vial, for reconstitution with bacteriostatic water; store at 2–8°C.